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As a transcriptional suppressor, Hes1 in the retina inhibits the differentiation of specific cell types and leads to excessive gliosis, increased inflammatory cytokine release, and ECM imbalance

Chapter 8 - inflammatory and oxidative stress markers in skeletal muscle of obese subjects

and inadequate standardization, as heterogeneous protocols (e.g., the use of arbitrary timepoints in the TEAC assay) impede reliable cross-study comparisons

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